In a neuromuscular junction, synaptic vesicles in the motor neuron contain which neurotransmitter?
Acetylcholine (Ach)
When an action potential arrives at the axon terminal of a motor neuron, which ion channels open?
Exocytosis
What means of membrane transport is used to release the neurotransmitter into the synaptic cleft?
Binding of the neurotransmitter causes chemically gated sodium channels to open in the motor end plate
How is acetylcholine (ACh) removed from the synaptic cleft?
All of the above (acetylcholinesterase (AChE; an enzyme) diffusion away from the synaptic cleft–a reuptake pump on the axon terminal)
The action potential on the muscle cell leads to contraction due to the release of calcium ions. Where are calcium ions stored in the muscle cell?
Terminal cisternae of the sarcoplasmic reticulum
What causes the release of calcium from the terminal cisternae of the sarcoplasmic reticulum within a muscle cell?
Arrival of an action potential
The binding of calcium to which molecule causes the myosin binding sites to be exposed?
Troponin
A myosin head binds to which molecule to form a cross bridge?
Actin
What causes the myosin head to disconnect from actin?
binding of ATP
What causes the power stroke?
release of ADP and Pi
The neuromuscular junction is a connection between a neuron and a
muscle fiber
The end of a neuron that contains acetylcholine-filled vesicles is called the
synaptic terminal
What is the synaptic cleft?
the space between the synaptic terminal and the motor end plate
Inside a neuron, acetylcholine is contained within
vesicles
What causes the vesicles inside a neuron to fuse with the plasma membrane?
an action potential in the neuron
Acetylcholine receptors are primarily located
on the motor end plate
Curare is a poison that prevents acetylcholine from binding to acetylcholine receptors. Which of the following is the most likely cause of death from curare exposure?
paralysis of skeletal muscles
An action potential in the muscle fiber causes
the muscle fiber to contract
The role of acetylcholinesterase in the neuromuscular junction is to _
remove acetylcholine from the synaptic cleft
What is the type of chemical reaction used to rebuild ADP into ATP?
dehydration synthesis
Which of the following processes produces molecules of ATP and has two pyruvic acid molecules as end products?
glyclysis
Which of the following processes produces 36 ATP?
Krebs cycle and oxidative phosphorylation
The “rest and recovery” period, where the muscle restores depleted reserves, includes all of the following processes EXCEPT
Pyruvic acid is converted back to lactic acid.
Which type of muscle fiber has a large quantity of glycogen and mainly uses glycolysis to synthesize ATP?
white fast twitch fibers
x

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